Study reveals the 3D structure of human uterine endometrium and adenomyosis tissue

(Niigata University) Recent advances in tissue-clearing-based 3D imaging have permitted researchers to establish a new baseline 3D structure of the endometrial glands, including the formation of a rhizome network in the stratum basalis that expands horizontally along the muscular layer. These findings have implications in understanding the mechanisms underlying normal endometrial tissue processes such as menstruation and fertilized egg implantation, and in clarifying the pathogenesis of endometr...